Type 2 diabetes - An Oral Drug that Can Both Protect Against Heart Failure and Lower Blood Glucose | Diabetes | Health | How Webs | United States | USA - How Webs

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Sunday, November 4, 2018

Type 2 diabetes - An Oral Drug that Can Both Protect Against Heart Failure and Lower Blood Glucose | Diabetes | Health | How Webs | United States | USA

Type 2 diabetes - An Oral Drug that Can Both Protect Against Heart Failure and Lower Blood Glucose | Diabetes | Health | How Webs | United States | USA

Type 2 diabetes | Dapagliflozin (Farxiga) is an SGLT2 inhibitor, given in the form of a pill for people who have been diagnosed with type 2 diabetes and who are used in combination with diet and exercise and sometimes with other medications. It works by separating more sugar into the urine by the kidneys. According to a study reported in October 2018 in the journal Cardiovascular Diabetology, the drug is also useful for the treatment of heart failure, a complication of Type 2 diabetes.

Type 2 diabetes - An Oral Drug that Can Both Protect Against Heart Failure and Lower Blood Glucose | Diabetes | Health | How Webs
Type 2 diabetes - An Oral Drug that Can Both Protect Against Heart Failure and Lower Blood Glucose | Diabetes | Health | How Webs

Heart failure occurs when the left side of the heart is unable to take blood from the lungs and send it quickly enough to the rest of the body.

The heart consists of muscle tissue that grows when it is stressed. The internal growth of this muscle provides a smaller space to collect blood that flows out of the lungs. This causes the heart to fail and fill the lungs with fluid from the blood.

In 2017, an estimated 26 million people worldwide had heart failure. In diabetes type 2, high blood sugar levels damage the heart and blood vessels and high blood pressure can develop. It is vital to bring the blood pressure value to a lower level to reduce the pressure on the heart. Heart attacks may not cause chest pain in people with type 2 diabetes because nerve damage reduces the sensation. That makes the prevention of heart disease even more necessary.



Researchers from Kobe University and various other research facilities in Japan looked at 58 people with type 2 diabetes and who also had heart failure. Dapagliflozin at a dose of 5 mg / day was added to their usual regimen. After six months, the muscle tissue that included the left side of the heart of the diabetic substance declined in size. Brain natriuretic peptide (BNP), a protein that is secreted by the heart cells in response to too many stretches, was reduced among participants whose BNP was extremely high. From this information, the researchers concluded that dapagliflozin can be useful for improving heart failure in people with type 2 diabetes.

The natriuretic peptide is effective in making the kidneys secrete potassium into the kidneys, reducing blood pressure and the amount of blood in the heart and blood vessels.

Dapagliflozin is given once daily, with or without food. It is prescribed as part of a general treatment plan that includes diet and exercise. Side effects are ...

  • urinary tract infections with yeast,
  • a stuffy nose with a sore throat,
  • often urinating in larger quantities and at night,
  • dizziness or a light feeling in the head,
  • ketoacidosis (check for ketones in the urine),
  • nausea and vomiting,
  • feeling very tired,
  • having trouble breathing
  • abdominal pain, and
  • kidney damage.

Although managing your disease can be very challenging, type 2 diabetes is not a condition you have to live with. You can make simple changes to your daily routine and lower both your weight and your blood sugar level. Hang in there, the longer you do it, the easier it gets.

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Type 2 diabetes - An Oral Drug that Can Both Protect Against Heart Failure and Lower Blood Glucose | Diabetes | Health | How Webs

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